Description

Glycine-N,N,o-D3 is a stable isotope-labeled derivative of the amino acid glycine, specifically deuterated at the amino and α-carbon positions. This high-purity compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as metabolic studies, internal standards in mass spectrometry, and NMR spectroscopy.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis to ensure accuracy in pharmaceutical bioanalysis and metabolomics.
• Metabolic Pathway Tracing: Employed in deuterium labeling studies to investigate glycine metabolism, amino acid turnover, and related biochemical pathways.
• NMR Spectroscopy: Serves as a valuable probe in nuclear magnetic resonance studies due to its distinct deuterium signals, aiding in structural elucidation and dynamic analysis.
• Pharmaceutical Research & Development: Utilized in the development and validation of analytical methods for new drug entities and in pharmacokinetic studies.
• Stable Isotope Labeling: Acts as a building block for the synthesis of more complex deuterated compounds for research and diagnostic purposes.
• Quality Control & Method Development: Integral in developing and verifying analytical methods in quality control laboratories to meet regulatory standards.

Basic Information

Product Name	Glycine-N,N,o-D3
CAS No.	4896-76-8
Molecular Formula	C₂D₃NO₂
Molecular Weight	78.08 g/mol
Synonyms	Glycine-2,2,2-d3; (Amino-d2)acetic-2-d acid; Glycine-d3; Deuterated Glycine; Aminoacetic-2,2,2-d3 acid; NSC 76045; Glycine (N,N-d2, o-d)
EINECS	Contact for details

Quality Control

Our Glycine-N,N,o-D3 is produced and tested under stringent quality management systems to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and solvent residues. We support compliance with relevant pharmacopeial guidelines and Good Manufacturing Practice (GMP) principles for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 98 atom % D
Assay (HPLC)	≥ 98.0%
Chemical Purity	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.