Description

Aristolochic Acid C CAS NO 4849-90-5 is a specific nitrophenanthrene carboxylic acid derivative, a member of the aristolochic acids family known for their distinct chemical structure. This high-purity reference standard is critical for analytical research, quality control, and toxicological studies due to its role as a marker compound. It is primarily required by research institutions, pharmaceutical quality assurance laboratories, and regulatory bodies engaged in safety assessment and method development.

Application

• Pharmaceutical Reference Standard: Serves as a certified external standard for the identification and quantification of aristolochic acids in herbal medicines and botanical extracts using HPLC, LC-MS, or TLC.
• Toxicological Research: Used in studies investigating the nephrotoxicity, carcinogenicity, and metabolic pathways of aristolochic acid compounds.
• Analytical Method Development: Essential for developing, validating, and calibrating sensitive analytical methods to detect and monitor aristolochic acid contamination in consumer products.
• Quality Control (QC) Testing: Employed by quality control laboratories in the herbal supplement and pharmaceutical industries to ensure product safety and compliance with regulatory limits on aristolochic acids.
• Biochemical Research: Utilized as a reagent in studies exploring DNA adduct formation and the mechanisms of action of nitrophenanthrene derivatives.

Basic Information

Product Name	Aristolochic Acid C
CAS No.	4849-90-5
Molecular Formula	C16H9NO6
Molecular Weight	311.25 g/mol
Synonyms	Aristolochic acid C; 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid; Aristolochic acid III; 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid; Aristolochic Acid A Methyl Ether; Nitrophenanthrene carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our Aristolochic Acid C is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the exacting standards required for reference materials. A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0% (Area Percent)
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.