Description

4-Methyl-2-Pentanone-1,1,1,3,3-D5 is a deuterated isotopologue of methyl isobutyl ketone (MIBK), a high-purity organic solvent and critical reagent. This compound is specifically valued for its role as a non-interfering internal standard and a labeled precursor in advanced analytical and synthetic chemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical instrumentation sectors who require precise quantification and mechanistic studies using techniques like NMR spectroscopy and mass spectrometry.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for accurate quantification of MIBK and related compounds in complex matrices.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent for NMR studies and as a labeled starting material for tracing reaction pathways and metabolic studies.
• Pharmaceutical Research & Development: Employed as a stable isotope-labeled intermediate in the synthesis of deuterated Active Pharmaceutical Ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Environmental & Forensic Analysis: Acts as a critical standard in the detection and precise measurement of solvent residues and environmental contaminants.
• Polymer & Coating Science: Utilized in research to study solvent behavior, polymerization kinetics, and coating formulations without spectral interference from protonated solvents.
• Organic Synthesis: Functions as a deuterium-labeled building block for synthesizing more complex labeled molecules for research and diagnostic applications.

Basic Information

Product Name	4-Methyl-2-Pentanone-1,1,1,3,3-D5
CAS No.	4840-81-7
Molecular Formula	C6H5D5O
Molecular Weight	105.17 g/mol
Synonyms	Methyl Isobutyl Ketone-d5; MIBK-d5; 4-Methylpentan-2-one-1,1,1,3,3-d5; Isobutyl Methyl Ketone-d5; Hexone-d5; 4-Methyl-2-oxopentane-1,1,1,3,3-d5; Deuterated Methyl Isobutyl Ketone; (3-Methylbutyl)methyl ketone-d5
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Pentanone-1,1,1,3,3-D5 is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % D), chemical purity, and identity confirmation. We adhere to relevant industry standards for high-purity reagents, ensuring reliability for your most sensitive analytical and synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong acids and oxidizing agents. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, Colorless Liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.