Description

2-Amino-4-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor in the development of novel pharmacologically active molecules, enabling research and production in high-value sectors. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical companies focused on creating new thiophene-based derivatives.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene scaffold for bioactive properties.
• Material Science Research: Serves as a monomer or precursor for developing organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and pigments for high-performance applications.
• Academic & Contract Research: A valuable reagent for methodological studies in heterocyclic chemistry and new synthetic route development.
• Custom Synthesis: A starting point for contract manufacturing organizations (CMOs) to produce bespoke, complex molecules for client projects.

Basic Information

Product Name	2-Amino-4-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	4815-36-5
Molecular Formula	C13H13NO2S
Molecular Weight	247.31 g/mol
Synonyms	Ethyl 2-Amino-4-phenylthiophene-3-carboxylate; 2-Amino-4-phenyl-3-thiophenecarboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-4-phenyl-, ethyl ester; 4-Phenyl-2-aminothiophene-3-carboxylic acid ethyl ester; Ethyl 2-amino-4-phenyl-3-thienoate; APTCE; 4815-36-5; NSC 403697
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Phenyl-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.