Description

Ethyl 2-Amino-5-Phenylthiophene-3-Carboxylate is a high-purity organic building block and heterocyclic intermediate of significant commercial importance. Its core value lies in its functionalized thiophene scaffold, which serves as a versatile precursor in advanced synthetic chemistry. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.
• Academic & R&D: Serves as a standard reagent in organic chemistry research for methodology development and heterocyclic compound library synthesis.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 2-Amino-5-Phenylthiophene-3-Carboxylate
CAS No.	4815-34-3
Molecular Formula	C13H13NO2S
Molecular Weight	247.31 g/mol
Synonyms	2-Amino-5-phenylthiophene-3-carboxylic acid ethyl ester; Ethyl 2-amino-5-phenyl-3-thiophenecarboxylate; 5-Phenyl-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-phenyl-, ethyl ester; 4815-34-3; 2-Amino-5-phenyl-3-thienoic acid ethyl ester; Ethyl α-amino-5-phenylthiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-5-Phenylthiophene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.