Description

2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing thiophene-based scaffolds, active pharmaceutical ingredients (APIs), and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a building block for developing organic semiconductors, conductive polymers, and other functional materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and organic pigments where the aminothiophene structure imparts specific color and stability properties.
• Academic & Industrial R&D: A fundamental reagent for method development, catalysis studies, and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	4815-32-1
Molecular Formula	C9H13NO2S
Molecular Weight	199.27 g/mol
Synonyms	Ethyl 2-Amino-5-methylthiophene-3-carboxylate; 2-Amino-5-methyl-3-thiophenecarboxylic acid ethyl ester; 5-Methyl-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-methyl-, ethyl ester; Ethyl 5-methyl-2-aminothiophene-3-carboxylate; 2-Amino-5-methyl-thiophene-3-carboxylic acid ethyl ester; AMTCAE; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methyl-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	88°C - 92°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.