Description

4-(Chloromethyl)-2-(4-Nitrophenyl)-1,3-Thiazole is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of key molecular scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel thiazole-containing drug candidates, particularly in antimicrobial and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the thiazole and nitrophenyl motifs.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization via the reactive chloromethyl group, enabling the construction of complex molecular architectures.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers and functional organic materials.
• Chemical Biology Probe Synthesis: Utilized in creating tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	4-(Chloromethyl)-2-(4-Nitrophenyl)-1,3-Thiazole
CAS No.	4771-32-8
Molecular Formula	C10H7ClN2O2S
Molecular Weight	254.69 g/mol
Synonyms	2-(4-Nitrophenyl)-4-(chloromethyl)thiazole; 4-(Chloromethyl)-2-(p-nitrophenyl)thiazole; 4-(Chloromethyl)-2-(4-nitrophenyl)-1,3-thiazole; 2-(4-Nitrophenyl)-4-(chloromethyl)-1,3-thiazole; 4-Chloromethyl-2-(4-nitrophenyl)thiazole; p-Nitrophenyl-4-chloromethylthiazole; 1,3-Thiazole, 4-(chloromethyl)-2-(4-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-(4-Nitrophenyl)-1,3-Thiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.