Description

1-(5-Hydroxyindolin-1-Yl)Ethanone is a specialized organic compound belonging to the indole derivative family, serving as a crucial building block in advanced chemical synthesis. Its value lies in its functionalized indoline core, which provides a versatile scaffold for constructing more complex molecules in pharmaceutical and agrochemical research. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the synthesis of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Biochemical Probe Synthesis: Serves as a starting material for creating labeled compounds and molecular probes used in biological studies and diagnostic assays.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	1-(5-Hydroxyindolin-1-Yl)Ethanone
CAS No.	4770-32-5
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	1-Acetyl-5-hydroxyindoline; 5-Hydroxy-1-indolinone; 5-Hydroxyindolin-1-yl ethanone; N-Acetyl-5-hydroxyindoline; 1-(5-Hydroxy-2,3-dihydro-1H-indol-1-yl)ethanone; 5-Hydroxy-1-acetylindoline; Ethanone, 1-(5-hydroxy-2,3-dihydro-1H-indol-1-yl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Hydroxyindolin-1-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Quality is verified through modern analytical techniques including HPLC, GC, NMR, and mass spectrometry. For specific project requirements, we offer material produced under cGMP guidelines and can support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.