Description

3-Nitro-1H-Indole is a versatile nitro-substituted indole derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science Research: Serves as a building block for creating organic semiconductors, dyes, and photochromic materials due to its electron-accepting nitro group.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a probe molecule in biochemical assays to understand biological pathways.
• Organic Synthesis Reagent: Utilized in various name reactions and as a starting material for further functionalization, such as reduction to aminoindoles or participation in cross-coupling reactions.

Basic Information

Product Name	3-Nitro-1H-Indole
CAS No.	4770-03-0
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	3-Nitroindole; 1H-Indole, 3-nitro-; Indole, 3-nitro-; 3-Nitro-1H-indole; NSC 404080; 3-Nitro-indole; 3-Nitro-1H-indole (9CI); 3-Nitroindol
EINECS	225-310-8

Quality Control

Our 3-Nitro-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	198 - 202 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.