Description

6-Nitro-1H-Indole-3-Carbonitrile is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring both nitro and nitrile functional groups on the indole core, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole scaffold.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photoactive materials in electronic applications.
• Academic & R&D: Employed in methodological studies and as a standard in heterocyclic chemistry research for novel ring-forming reactions.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.

Basic Information

Product Name	6-Nitro-1H-Indole-3-Carbonitrile
CAS No.	4769-99-7
Molecular Formula	C9H5N3O2
Molecular Weight	187.16 g/mol
Synonyms	6-Nitroindole-3-carbonitrile; 3-Cyano-6-nitroindole; 1H-Indole-3-carbonitrile, 6-nitro-; 6-Nitro-1H-indole-3-carbonitrile; 6-Nitroindole-3-CN
EINECS	Contact for details

Quality Control

Our 6-Nitro-1H-Indole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.