Description

4-Nitroindole is a versatile and high-value heterocyclic aromatic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique nitro-substituted indole structure makes it an essential building block for the development of complex molecules, particularly in pharmaceutical research and fine chemical synthesis. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, including kinase inhibitors, receptor modulators, and other bioactive molecules targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive indole scaffold.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photochromic materials where the nitro group acts as an electron acceptor.
• Chemical Biology & Proteomics: Employed as a probe or tag in biochemical assays and for studying protein-ligand interactions.
• Academic & Contract Research: Fundamental reagent in university and CRO laboratories for methodological development in organic synthesis and heterocyclic chemistry.
• Fine Chemical Synthesis: Intermediate for producing more complex indole derivatives, such as tryptamines and other alkaloid-like structures.

Basic Information

Product Name	4-Nitroindole
CAS No.	4769-97-5
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	4-Nitro-1H-indole; 1H-Indole, 4-nitro-; Indole, 4-nitro-; 4-Nitroindol; 4-Nitro-indole; 4-NO2-Indole; 4-Nitrogen-indole; NSC 406120
EINECS	225-309-5

Quality Control

Our 4-Nitroindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each shipment. Our quality commitment ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.