Description

1-(4-Nitro-1H-Indol-3-Yl)-Ethanone is a specialized nitro-substituted indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular structure makes it a valuable building block for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies focused on innovative drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel indole-based drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Building block for developing new crop protection agents and herbicides that leverage the indole scaffold.
• Organic Synthesis: Versatile starting material for constructing complex heterocycles, including fused ring systems, via its reactive nitro and carbonyl functional groups.
• Material Science: Used in the research and development of specialty chemicals, dyes, and advanced organic materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1-(4-Nitro-1H-Indol-3-Yl)-Ethanone
CAS No.	4769-95-3
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	3-Acetyl-4-nitroindole; 4-Nitro-3-acetylindole; 1-(4-Nitro-1H-indol-3-yl)ethanone; 3-Acetyl-4-nitro-1H-indole; Ethanone, 1-(4-nitro-1H-indol-3-yl)-; 4-Nitroindol-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Nitro-1H-Indol-3-Yl)-Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and synthesis applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements of pharmaceutical R&D and advanced organic synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.