Description

4-Hydroxybenzoic Acid [Carboxyl-14C] is a carbon-14 radiolabeled derivative of the common phenolic acid, specifically labeled at the carboxyl carbon position. This compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to trace the compound's fate in biological and environmental systems with high sensitivity. It is a critical tool for scientists in pharmaceutical R&D, agrochemical development, and environmental science who require definitive data on compound absorption, distribution, metabolism, and excretion (ADME).

Application

• Pharmaceutical ADME Studies: Tracing the metabolic pathways and excretion profiles of 4-hydroxybenzoic acid and its derivatives in vivo.
• Agrochemical Research: Investigating the environmental fate, degradation, and plant uptake of phenolic compounds used in crop protection.
• Biochemical Pathway Analysis: Elucidating specific enzymatic reactions and biosynthetic routes involving benzoic acid derivatives.
• Tracer Studies in Microbiology: Studying the metabolism of aromatic compounds by microorganisms for biodegradation or synthetic biology applications.
• Radiochemical Synthesis: Serving as a labeled building block for the synthesis of more complex radiolabeled molecules for research.
• Environmental Fate Studies: Monitoring the persistence, transformation, and mobility of phenolic contaminants in soil and water systems.

Basic Information

Product Name	4-Hydroxybenzoic Acid [Carboxyl-14C]
CAS No.	4752-47-0
Molecular Formula	C7H6O3 (with 14C at C1)
Molecular Weight	~138.12 g/mol (exact mass depends on specific activity)
Synonyms	p-Hydroxybenzoic Acid-[carboxy-14C]; 4-Carboxy-14C-phenol; Benzoic-14C acid, 4-hydroxy-; [Carboxyl-14C]-Paraben precursor; 14C-pHBA; Radioactive 4-hydroxybenzoic acid; 4-HBA-[14C]; p-Hydroxy[14C]benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxybenzoic Acid [Carboxyl-14C] is manufactured and analyzed under strict quality systems to ensure radiochemical purity, chemical purity, and specific activity meet the stringent requirements of research applications. Our products undergo rigorous quality testing, including HPLC with radiometric detection. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specific activity, radiochemical purity, chemical purity, and solvent composition.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to minimize radiolytic decomposition and oxidation. This product is light-sensitive and easily oxidized. Users must handle all radioactive materials in accordance with local radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	White to Off-White Solid or Solution
Identification (IR/HPLC)	Conforms to Reference Standard
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 95%
Solvent	Ethanol, Toluene, or Custom (Specified on COA)
Concentration	1.0 mCi/mL or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.