Description

tert-Butylphosphonic Dichloride is a high-purity organophosphorus reagent primarily used as a key synthetic intermediate. Its value lies in its role as a versatile building block for introducing the sterically hindered tert-butylphosphonate group into more complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Synthesis of novel drug candidates, particularly those targeting kinase inhibition or acting as prodrugs.
• Agrochemical Synthesis: Production of advanced herbicides, fungicides, and plant growth regulators containing phosphonate moieties.
• Ligand Precursor: Manufacture of specialized phosphine ligands for catalysis and coordination chemistry in industrial processes.
• Polymer Modification: Used as a monomer or modifier in the synthesis of flame-retardant polymers and specialty resins.
• Material Science Research: Key reagent for developing metal-organic frameworks (MOFs) and surface-modifying agents.
• Chemical Synthesis: Versatile starting material for preparing tert-butylphosphonic acids, esters, and amides through controlled hydrolysis or alcoholysis.

Basic Information

Product Name	tert-Butylphosphonic Dichloride
CAS No.	4707-95-3
Molecular Formula	C4H9Cl2OP
Molecular Weight	174.99 g/mol
Synonyms	Phosphonic dichloride, P,P-di-tert-butyl; tert-Butylphosphonyl Dichloride; Di-tert-butylphosphinic Chloride; (tert-Butyl)phosphonic Dichloride; 2-Methyl-2-propanephosphonic Dichloride; TBPD; t-BuPOCl2
EINECS	225-189-6

Quality Control

Our tert-Butylphosphonic Dichloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and titration methods, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.