Description

2-Phthalimidoacrylic Acid is a specialized organic compound featuring a phthalimide-protected amino group conjugated with an acrylic acid moiety. This unique structure makes it a valuable high-purity synthetic intermediate for the production of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in the synthesis of active pharmaceutical ingredients (APIs), peptidomimetics, and other advanced organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Synthesis: Used to introduce protected amino acid analogs into peptide chains for drug discovery.
• Organic Synthesis Reagent: Serves as a versatile precursor for Michael addition reactions and other carbon-carbon bond forming processes.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and synthetic pathways.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	2-Phthalimidoacrylic Acid
CAS No.	4702-17-4
Molecular Formula	C11H7NO4
Molecular Weight	217.18 g/mol
Synonyms	2-(1,3-Dioxoisoindolin-2-yl)acrylic Acid; 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acrylic Acid; N-Acryloylphthalimide; Phthalimidoacrylic Acid; 2-Phthalimido-2-propenoic Acid; Acrylic acid, 2-phthalimido-; 2-Propenoic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-
EINECS	225-168-1

Quality Control

Our 2-Phthalimidoacrylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.