Description

5-Bromothiophene-2-Carbaldehyde is a versatile and high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical precursor in the development of complex molecules, enabling the introduction of both aldehyde and bromine functional groups for further derivatization. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the creation of novel fungicides, herbicides, and insecticides, leveraging the thiophene scaffold for bioactivity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and organic semiconductors used in OLEDs, OFETs, and solar cells.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology & Probe Synthesis: Utilized to create fluorescent probes or molecular tags for studying biological systems.
• Cross-Coupling Reactions: The bromine moiety makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	5-Bromothiophene-2-Carbaldehyde
CAS No.	4701-17-1
Molecular Formula	C5H3BrOS
Molecular Weight	191.05 g/mol
Synonyms	2-Bromo-5-formylthiophene; 5-Bromo-2-thiophenecarboxaldehyde; 5-Bromothiophene-2-carboxaldehyde; 2-Formyl-5-bromothiophene; 5-Bromo-2-thienylcarboxaldehyde; 5-Bromothienyl-2-aldehyde; 2-Thiophenecarboxaldehyde, 5-bromo-
EINECS	225-173-6

Quality Control

Our 5-Bromothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.