Description

Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7R)-Rel- (9Ci) is a high-purity, stereochemically defined chlorinated norbornane derivative. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of complex molecules with specific three-dimensional architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemistry and reliable quality for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the rigid bicyclic framework of norbornane.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the chlorinated norbornane structure can confer specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Monomer: Potential monomer for creating polymers with unique thermal and mechanical properties derived from the strained bicyclic system.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct complex polycyclic structures in medicinal and process chemistry.
• Flavor and Fragrance Industry: Intermediate for the synthesis of certain terpene-based aroma chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7R)-Rel- (9Ci)
CAS No.	4660-48-4
Molecular Formula	C7H10Cl2
Molecular Weight	165.06 g/mol
Synonyms	(1R,2S,4S,7R)-2,7-Dichloronorbornane; rel-(1R,2S,4S,7R)-2,7-Dichlorobicyclo[2.2.1]heptane; 2,7-Dichloronorbornane; 2,7-Dichlorobicyclo[2.2.1]heptane; endo,endo-2,7-Dichloronorbornane; Bicyclo[2.2.1]heptane, 2,7-dichloro-, (1R,2S,4S,7R)-rel-; 4660-48-4
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7R)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.