Description

Methyl 2-Aminothiophene-3-Carboxylate is a versatile heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for the synthesis of novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, including kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the thiophene scaffold's bioactivity.
• Material Science Research: Serves as a monomer or building block for creating conjugated polymers and organic electronic materials due to its electron-rich thiophene core.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized heterocyclic dyes and organic pigments.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical spaces in medicinal chemistry.
• Custom Synthesis: A starting point for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	Methyl 2-Aminothiophene-3-Carboxylate
CAS No.	4651-81-4
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	2-Amino-3-thiophenecarboxylic acid methyl ester; Methyl 2-amino-3-thiophenecarboxylate; 2-Aminothiophene-3-carboxylic acid methyl ester; 3-Carbomethoxy-2-aminothiophene; 2-Amino-3-(methoxycarbonyl)thiophene; Methyl 2-aminothiophene-3-carboxylate; 2-Amino-3-thiophenecarboxylic acid, methyl ester
EINECS	225-073-6

Quality Control

Our Methyl 2-Aminothiophene-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.