Description

(4-Bromophenyl)Dimethylphosphine Oxide is a versatile organophosphorus compound featuring a brominated aromatic ring, making it a valuable intermediate in advanced chemical synthesis. Its unique structure provides a reactive handle for cross-coupling reactions and serves as a key precursor for ligands and functional materials. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogen and phosphine oxide functionalities.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphine ligands used in homogeneous catalysis, such as palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Material Science Research: Employed in the creation of organic electronic materials, flame retardants, and polymers where bromine and phosphorus impart specific properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the (4-bromophenyl)dimethylphosphine oxide moiety into more complex molecular architectures.
• Academic & Industrial R&D: A critical compound for methodological development in organic chemistry and process chemistry within research laboratories.

Basic Information

Product Name	(4-Bromophenyl)Dimethylphosphine Oxide
CAS No.	4648-59-3
Molecular Formula	C8H10BrOP
Molecular Weight	233.04 g/mol
Synonyms	Dimethyl(4-bromophenyl)phosphine oxide; (p-Bromophenyl)dimethylphosphine oxide; 4-Bromophenyldimethylphosphine oxide; Phosphine oxide, dimethyl(4-bromophenyl)-; 1-Bromo-4-(dimethylphosphoryl)benzene; (4-Bromophenyl)dimethylphosphine oxide; (4-Bromophenyl)dimethylphosphane oxide
EINECS	Contact for details

Quality Control

Our (4-Bromophenyl)Dimethylphosphine Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.