Description

Ritodrine Hydrochloride CAS NO 4635-27-2 is a selective β2-adrenergic receptor agonist, primarily used as a tocolytic agent. Its core value lies in its ability to inhibit uterine contractions, making it a critical pharmaceutical active ingredient. This compound is essential for manufacturers in the pharmaceutical industry, particularly those developing and producing medications for preterm labor. Consistent quality and reliable supply are paramount for ensuring the safety and efficacy of the final drug product.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key component in tocolytic medications for the management of preterm labor.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Research & Development: Used in preclinical and clinical studies focused on uterine physiology, adrenergic receptors, and obstetric pharmacology.
• Formulation Development: Employed in the development of various dosage forms, such as injectable solutions and oral tablets.
• Pharmacopoeial Testing: Utilized in compliance testing against standards set by pharmacopoeias like USP (United States Pharmacopeia) and EP (European Pharmacopoeia).

Basic Information

Product Name	Ritodrine Hydrochloride
CAS No.	4635-27-2
Molecular Formula	C17H21NO3 • HCl
Molecular Weight	323.82 g/mol
Synonyms	Ritodrine HCl; Yutopar; N-(p-Hydroxyphenethyl)norphenylephrine Hydrochloride; (±)-erythro-1-(4-Hydroxyphenyl)-2-{[2-(4-hydroxyphenyl)ethyl]amino}propan-1-ol Hydrochloride; DL-erythro-1-(4-Hydroxyphenyl)-2-{[2-(4-hydroxyphenyl)ethyl]amino}-1-propanol Hydrochloride; (±)-erythro-α-[[2-(4-Hydroxyphenyl)ethyl]amino]methyl]-4-hydroxybenzenemethanol Hydrochloride; Pre-Par; Uterine Relaxant 501
EINECS	Contact for details

Quality Control

Our Ritodrine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards, typically referencing pharmacopoeial specifications such as USP or EP. Key parameters including identity, assay, related substances, and residual solvents are rigorously controlled. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.