Description

3-Thiolquinuclidine is a specialized heterocyclic building block featuring a quinuclidine scaffold with a thiol functional group. This compound matters for its unique reactivity profile, serving as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. Industries that need this high-value chemical include pharmaceutical companies, agrochemical R&D labs, and advanced material science researchers focused on creating novel ligands and catalysts. Its distinct structure offers chemists a versatile handle for constructing nitrogen- and sulfur-containing target compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and neurological targets.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Catalyst & Ligand Precursor: Serves as a starting material for developing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction methodologies and constructing complex molecular architectures.
• Material Science: Investigated for the development of advanced polymers and functional materials where the thiol group enables specific cross-linking or surface modification.

Basic Information

Product Name	3-Thiolquinuclidine
CAS No.	4595-82-8
Molecular Formula	C7H13NS
Molecular Weight	143.25 g/mol
Synonyms	Quinuclidine-3-thiol; 3-Mercaptoquinuclidine; 3-Quinuclidinethiol; 1-Azabicyclo[2.2.2]octane-3-thiol; 3-Thioquinuclidine; 3-SH-Quinuclidine; 4595-82-8; NSC 163044
EINECS	Contact for details

Quality Control

Our 3-Thiolquinuclidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be kept sealed and only opened in an inert environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.