Description

5-Formyl-2-Thiophenecarboxylic Acid is a high-purity heterocyclic building block essential for advanced organic synthesis. Its bifunctional structure, featuring both a formyl and a carboxylic acid group on a thiophene core, makes it a versatile precursor for constructing complex molecules. This compound is critically important for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chelating ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material processing.
• Functional Material Development: Employed in the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials for electronic and photonic applications.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new heterocyclic compounds and reaction methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty additives.

Basic Information

Product Name	5-Formyl-2-Thiophenecarboxylic Acid
CAS No.	4565-31-5
Molecular Formula	C6H4O3S
Molecular Weight	156.16 g/mol
Synonyms	2-Formylthiophene-5-carboxylic Acid; 2-Thiophenecarboxylic acid, 5-formyl-; 5-Carboxy-2-thiophenecarboxaldehyde; Thiophene-2,5-dicarboxaldehyde (misnomer); 5-Formylthiophene-2-carboxylic Acid; 2-Carboxy-5-formylthiophene; 5-Aldehydothiophene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 5-Formyl-2-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. For long-term storage, consider using an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.