Description

4,5α-Epoxy-3-Hydroxy-6-Methoxy-α,17-Dimethyl-α-Propyl-6β,14-Ethenomorphinan-7-Methanol is a high-purity synthetic organic compound of significant interest in advanced pharmaceutical research and development. This complex morphinan derivative serves as a critical intermediate or reference standard for the synthesis and analytical characterization of specialized active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel therapeutic agents within the opioid receptor modulator class.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex, target-specific pharmaceutical compounds.
• Reference Standard: Used as a high-purity standard in analytical methods (HPLC, GC-MS) for quality control and regulatory compliance of related APIs.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) and receptor binding affinities.
• Process Development: Utilized in the scale-up and optimization of synthetic routes within process chemistry departments.
• Academic Research: Supports advanced organic chemistry and medicinal chemistry research in university and institutional laboratories.
• Custom Synthesis: Acts as a starting material for the custom synthesis of novel analogs and derivatives for proprietary research programs.

Basic Information

Product Name	4,5α-Epoxy-3-Hydroxy-6-Methoxy-α,17-Dimethyl-α-Propyl-6β,14-Ethenomorphinan-7-Methanol
CAS No.	4562-22-5
Molecular Formula	C24H31NO4
Molecular Weight	397.51 g/mol
Synonyms	6,14-Ethenomorphinan-7-methanol, 4,5-epoxy-3-hydroxy-6-methoxy-α,17-dimethyl-α-propyl-; 7α-(1-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrothebaine; 7α-(1-Hydroxy-1-methylbutyl)-6,14-endo-ethenotetrahydrooripavine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,5α-Epoxy-3-Hydroxy-6-Methoxy-α,17-Dimethyl-α-Propyl-6β,14-Ethenomorphinan-7-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.