Description

Diphenylphosphine Oxide is a versatile organophosphorus compound widely used as a key intermediate in advanced chemical synthesis. Its significance lies in its role as a crucial ligand precursor and building block for pharmaceuticals, agrochemicals, and specialty materials. This product is essential for R&D and production teams in the pharmaceutical, fine chemical, and material science industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phosphine oxide or phosphine ligand motifs.
• Ligand Synthesis: Serves as a fundamental starting material for the preparation of sophisticated phosphine ligands used in homogeneous catalysis, such as cross-coupling reactions.
• Agrochemical Production: Used in the manufacture of certain herbicides, fungicides, and plant growth regulators where the diphenylphosphine oxide moiety is integral to biological activity.
• Flame Retardant Synergist: Acts as an additive or co-reactant in flame-retardant formulations for polymers and plastics.
• Material Science: Employed in the research and development of advanced materials, including organic electronics and metal-organic frameworks (MOFs).
• Organic Synthesis Reagent: Utilized in various organic transformations, including the preparation of ylides and as a stabilizing group in synthetic chemistry.

Basic Information

Product Name	Diphenylphosphine Oxide
CAS No.	4559-70-0
Molecular Formula	C12H11OP
Molecular Weight	202.19 g/mol
Synonyms	Diphenylphosphine oxide; Diphenylphosphinous acid; DPPO; Oxodiphenylphosphine; P,P-Diphenylphosphinous acid; Phosphine oxide, diphenyl-; (Oxo)diphenylphosphine; Diphenylphosphane oxide
EINECS	224-927-6

Quality Control

Our Diphenylphosphine Oxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay (HPLC), identification (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.