Description

Ethanethiol, 2-Phthalimido- CAS NO 4490-75-9 is a specialized organosulfur compound featuring a phthalimide-protected thiol group, serving as a versatile building block in advanced organic synthesis. Its core value lies in its ability to act as a protected thiol reagent, enabling the controlled introduction of sulfur-containing functional groups into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities where precise sulfur chemistry is required.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) containing thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that utilize sulfur-based bioactive moieties.
• Peptide Chemistry: Serves as a cysteine analog or protecting group reagent in the synthesis of modified peptides and peptidomimetics.
• Material Science Research: Employed in the development of novel polymers, ligands for metal catalysis, and functionalized surfaces.
• Chemical Biology Probes: Useful for creating activity-based probes or bioconjugation handles that target thiol-reactive sites in biological systems.

Basic Information

Product Name	Ethanethiol, 2-Phthalimido-
CAS No.	4490-75-9
Molecular Formula	C₁₀H₉NO₂S
Molecular Weight	207.25 g/mol
Synonyms	2-(Phthalimido)ethanethiol; N-(2-Mercaptoethyl)phthalimide; 2-Phthalimidoethanethiol; 2-(1,3-Dioxoisoindolin-2-yl)ethanethiol; Phthalimidylethanethiol; 2-(Phthalimido)ethyl mercaptan; N-(2-Sulfanylethyl)phthalimide; 4490-75-9
EINECS	Contact for details

Quality Control

Our Ethanethiol, 2-Phthalimido- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	98 - 102 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.