Description

1-Deuteriopropan-2-One is a deuterium-labeled isotopologue of acetone, a crucial analytical standard and reagent in modern research. This compound is essential for applications requiring precise tracking and quantification using spectroscopic and mass spectrometric techniques. It is primarily needed by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard, solvent in NMR spectroscopy, and a precursor in the synthesis of labeled compounds.

Application

• NMR Spectroscopy Solvent: Used as a deuterated solvent for proton NMR, providing a non-interfering signal for accurate structural analysis of organic molecules.
• Mass Spectrometry Internal Standard: Serves as a critical internal standard in quantitative GC-MS and LC-MS analyses for accurate measurement of acetone and related metabolites.
• Isotopic Tracer Studies: Employed in metabolic pathway research and pharmacokinetic studies to trace the fate of acetone and its derivatives in biological systems.
• Chemical Synthesis Intermediate: Acts as a building block for the synthesis of more complex deuterium-labeled compounds used in research and development.
• Analytical Reference Standard: Provides a certified reference material for calibrating instruments and validating analytical methods in quality control laboratories.
• Polymer and Material Science Research: Used in studies investigating polymerization kinetics and solvent interactions where isotopic labeling is required.

Basic Information

Product Name	1-Deuteriopropan-2-One
CAS No.	4468-52-4
Molecular Formula	C3H5DO
Molecular Weight	59.09 g/mol
Synonyms	Acetone-d1; Deuterated Acetone (mono-deuterated); (Deuteromethyl) methyl ketone; 2-Propanone-1-d1; Methyl-d1 ketone; Propan-2-one-1-d; Deuterioacetone; 1-Deuteroacetone
EINECS	Contact for details

Quality Control

Our 1-Deuteriopropan-2-One is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure high isotopic purity and chemical integrity, with specifications typically meeting or exceeding standard research-grade requirements. A Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and relevant spectroscopic data is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept upright and sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to reference spectrum
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.