Description

1H-Indole-1-Acetonitrile(9Ci) is a versatile indole-based nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive nitrile group attached to the indole nitrogen, enabling the construction of complex heterocyclic frameworks and pharmacophores. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of indole alkaloid derivatives and potential drug candidates targeting central nervous system disorders.
• Agrochemical Synthesis: Building block for creating novel plant growth regulators and pesticides with indole-based structures.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing enzyme inhibitors, fluorescent probes, and bioconjugation reagents.
• Academic & R&D Laboratories: Fundamental reagent for methodological studies in heterocyclic and nitrile chemistry.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and complex fragrance compounds.

Basic Information

Product Name	1H-Indole-1-Acetonitrile(9Ci)
CAS No.	4414-73-7
Molecular Formula	C10H8N2
Molecular Weight	156.19 g/mol
Synonyms	1H-Indole-1-acetonitrile; Indole-1-acetonitrile; 1-(Cyanomethyl)indole; (1H-Indol-1-yl)acetonitrile; 1-Indolylacetonitrile; N-Cyanomethylindole; 4414-73-7; 1H-Indole-1-ethanenitrile
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Acetonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring suitability for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.