Description

1H-Isoindole-1,3(2H)-Dione, 2-(2,5-Dioxo-1-Pyrrolidinyl)- is a high-purity organic compound widely recognized as a versatile chemical building block and cross-linking agent. Its core value lies in its reactive maleimide and phthalimide functional groups, enabling robust chemical modifications and polymer synthesis. This product is essential for researchers and manufacturers in the pharmaceutical, advanced materials, and specialty polymer industries seeking to develop novel compounds and enhance material properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring maleimide conjugation for targeted therapies.
• Polymer Cross-Linking Agent: Used to create thermally stable and mechanically robust cross-linked networks in specialty polymers, resins, and coatings.
• Bioconjugation Reagent: Facilitates the site-specific labeling and modification of proteins, antibodies, and peptides for diagnostic and therapeutic applications.
• Advanced Material Synthesis: A critical monomer for producing polyimides and other high-performance polymers used in electronics, aerospace, and automotive components.
• Organic Synthesis Building Block: Employed in research and development for constructing complex heterocyclic compounds and functional materials.
• Adhesive & Sealant Formulations: Enhances the durability and thermal resistance of industrial adhesives and sealants.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 2-(2,5-Dioxo-1-Pyrrolidinyl)-
CAS No.	4403-40-1
Molecular Formula	C12H8N2O4
Molecular Weight	244.20 g/mol
Synonyms	N-(2,5-Dioxo-1-pyrrolidinyl)phthalimide; 1-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-2,5-pyrrolidinedione; 2-(2,5-Dioxopyrrolidin-1-yl)isoindoline-1,3-dione; N-Phthalimidosuccinimide; N-(Phthalimido)succinimide; NPS; Maleimidophthalimide; Bisimide cross-linker
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione, 2-(2,5-Dioxo-1-Pyrrolidinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.