Description

Cyclobutyl Bromide is a versatile organic halide building block essential for advanced chemical synthesis. Its strained four-membered ring structure and reactive bromine atom make it a valuable intermediate for constructing complex molecular architectures. This compound is particularly sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing cyclobutane rings for drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its reactivity to introduce the cyclobutyl moiety.
• Organic Synthesis Reagent: Serves as an alkylating agent in various organic transformations, including nucleophilic substitution and cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers and advanced materials where the cyclobutane structure imparts specific physical properties.
• Ligand and Catalyst Preparation: Utilized for modifying ligands and synthesizing organometallic complexes for catalytic applications.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes and tags used in biochemical and cellular studies.

Basic Information

Product Name	Cyclobutyl Bromide
CAS No.	4399-47-7
Molecular Formula	C4H7Br
Molecular Weight	135.00 g/mol
Synonyms	Bromocyclobutane; Cyclobutane, bromo-; Cyclobutylbromide; NSC 9375; 1-Bromocyclobutane; Cyclobutyl bromide; Bromane, cyclobutyl-
EINECS	224-525-7

Quality Control

Our Cyclobutyl Bromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and impurity profiling, to meet the exacting standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.