Description

2-Iodopropene is a versatile organoiodine compound, a key building block in organic synthesis valued for its reactivity as an alkylating agent and its utility in cross-coupling reactions. Its importance lies in enabling the efficient construction of complex molecular frameworks, particularly in the development of pharmaceuticals and advanced materials. This high-purity intermediate is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring propene-derived side chains.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and other crop protection agents where its iodine moiety facilitates key bond-forming steps.
• Material Science: Acts as a monomer or functionalization agent in the production of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: A valuable substrate in Heck, Stille, and Suzuki-Miyaura cross-coupling reactions to form new carbon-carbon bonds.
• Alkylation Agent: Employed in organic synthesis to introduce the 2-iodopropene group into target molecules under controlled conditions.
• Research & Development: A fundamental reagent in academic and industrial laboratories for methodological development and exploring new synthetic routes.

Basic Information

Product Name	2-Iodopropene
CAS No.	4375-96-6
Molecular Formula	C3H5I
Molecular Weight	167.98 g/mol
Synonyms	2-Iodopropene; 1-Iodo-1-propene; 1-Propene, 1-iodo-; 1-Iodopropene; 1-Iodoprop-1-ene; Prop-1-en-1-yl iodide; Isopropenyl iodide; 2-Iodoprop-1-ene
EINECS	Contact for details

Quality Control

Our 2-Iodopropene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including GC, HPLC, and NMR, to confirm identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C to maximize stability. The container should be kept tightly sealed under an inert atmosphere to prevent degradation and should be clearly labeled with handling precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Specific Gravity	1.80 - 1.85

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.