Description

(3-Thiophen-2-Ylmethyl-5-Thioxo-1,5-Dihydro-[1,2,4]Triazol-4-Yl)-Acetic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring fused triazole and thiophene rings, makes it a valuable precursor for developing novel pharmacologically active compounds and functional materials. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a building block for organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its electron-rich thiophene and triazole components.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Coordination Chemistry: Functions as a ligand for metal complexes, useful in catalysis and the development of new catalytic systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific applications.

Basic Information

Product Name	(3-Thiophen-2-Ylmethyl-5-Thioxo-1,5-Dihydro-[1,2,4]Triazol-4-Yl)-Acetic Acid
CAS No.	4363-99-9
Molecular Formula	C10H9N3O2S2
Molecular Weight	267.33 g/mol
Synonyms	4-(Carboxymethyl)-3-[(thiophen-2-yl)methyl]-1H-1,2,4-triazole-5(4H)-thione; 2-{[3-[(Thiophen-2-yl)methyl]-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-4-yl]}acetic acid; (3-((Thiophen-2-yl)methyl)-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-4-yl)acetic acid; 4363-99-9; 1,2,4-Triazole-4-acetic acid, 3-(2-thienylmethyl)-5-thioxo-1,5-dihydro-; 3-(2-Thienylmethyl)-5-thioxo-1,5-dihydro-1,2,4-triazole-4-acetic acid
EINECS	Contact for details

Quality Control

Our (3-Thiophen-2-Ylmethyl-5-Thioxo-1,5-Dihydro-[1,2,4]Triazol-4-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all specifications are available upon request, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.