Description

2-Chloroethanethiol is a versatile organosulfur compound with a reactive thiol group and a chloroethyl moiety. This dual functionality makes it a valuable intermediate for introducing sulfur-containing groups into target molecules, enabling the synthesis of a wide range of specialty chemicals. It is primarily sought after by research and development laboratories, pharmaceutical manufacturers, and agrochemical producers for applications in organic synthesis and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether linkages or requiring specific sulfur-based functionalization.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides where the thiol group acts as a reactive handle for creating novel compounds.
• Polymer Modification: Serves as a chain transfer agent or a functional monomer to introduce thiol groups into polymer backbones, altering material properties like adhesion and cross-linking potential.
• Chemical Research & Development: A crucial reagent in organic synthesis for constructing complex molecules, studying reaction mechanisms, and developing new synthetic methodologies.
• Ligand Precursor: Used in the preparation of sulfur-containing ligands for metal catalysis and coordination chemistry.
• Surface Functionalization: Employed to modify material surfaces by creating self-assembled monolayers (SAMs) or to impart specific chemical reactivity.

Basic Information

Product Name	2-Chloroethanethiol
CAS No.	4325-97-7
Molecular Formula	C2H5ClS
Molecular Weight	96.58 g/mol
Synonyms	2-Chloro-1-ethanethiol; 2-Chloroethyl mercaptan; β-Chloroethyl mercaptan; 1-Chloro-2-mercaptoethane; 2-Chloroethanethiol; Chloroethyl mercaptan; (2-Chloroethyl)thiol; Mercaptoethyl chloride; NSC 8815
EINECS	224-376-5

Quality Control

Our 2-Chloroethanethiol is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including assay by GC or HPLC and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat, sparks, and open flames. Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep container tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	1.18 - 1.20
Refractive Index (20°C)	1.495 - 1.505

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.