Description

Diethyl Malonate-D2 is a deuterated analog of diethyl malonate, where two hydrogen atoms are replaced by deuterium atoms. This isotopic labeling is critical for applications requiring enhanced chemical stability, reduced metabolic degradation, or specific spectroscopic properties. It serves as a valuable building block in the synthesis of deuterated pharmaceuticals, agrochemicals, and advanced materials for the life sciences and specialty chemical industries.

Application

• Deuterated Pharmaceutical Intermediates: Used in the synthesis of Active Pharmaceutical Ingredients (APIs) with deuterium incorporation for improved metabolic stability and pharmacokinetic profiles (Deuterium Drug Discovery).
• NMR Spectroscopy & Mass Spectrometry: Acts as an internal standard or a tracer in analytical chemistry for quantitative analysis and metabolic pathway studies.
• Deuterated Agrochemicals: Employed in the research and development of labeled pesticides and herbicides to study environmental fate and degradation.
• Organic Synthesis & Catalysis Research: A key reagent in deuterium-labeling reactions and mechanistic studies in academic and industrial R&D laboratories.
• Specialty Polymer & Material Science: Used to create deuterated monomers for polymers with specific optical or physical properties used in advanced material applications.
• Flavor & Fragrance Industry: Potential use in synthesizing deuterated aroma chemicals for research into odor perception and stability.

Basic Information

Product Name	Diethyl Malonate-D2
CAS No.	4303-49-5
Molecular Formula	C7H10D2O4
Molecular Weight	162.18 g/mol
Synonyms	Diethyl Malonate-d2; Diethyl Propanedioate-d2; Diethyl (2,2-dideuterio)malonate; Malonic Acid-d2 Diethyl Ester; Diethyl Malonate (D2); Diethyl 2,2-Dideuteriomalonate; Propanedioic-2,2-d2 acid, diethyl ester; Ethyl Malonate-d2
EINECS	Contact for details

Quality Control

Our Diethyl Malonate-D2 CAS 4303-49-5 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and GC-MS, to ensure high isotopic purity and chemical purity. Certificates of Analysis (COA) detailing isotopic enrichment (D atom %), chemical assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at room temperature for shorter periods. Keep container tightly sealed when not in use to minimize moisture absorption and prevent volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Isotopic Purity (D atom %)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.