Description

2-Keto-4-Mercaptobutyric Acid is a versatile sulfur-containing keto acid with significant utility in organic synthesis and biochemical research. Its unique structure, featuring both a ketone and a thiol group, makes it a valuable intermediate for constructing complex molecules and studying metabolic pathways. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical, flavor & fragrance, and fine chemical industries seeking to develop novel compounds or modify existing ones.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfur or modified amino acid structures.
• Flavor & Fragrance Precursor: Used in the production of sulfur-containing flavor compounds that contribute to meaty, roasted, or savory notes in food products.
• Biochemical Research: Serves as a substrate or intermediate in studies of metabolic pathways, enzyme mechanisms, and the biochemistry of sulfur compounds.
• Organic Synthesis Reagent: Utilized as a versatile synthon for introducing thiol and carboxylic acid functionalities in complex organic molecules.
• Chelating Agent Synthesis: Acts as a precursor for the development of novel chelating agents and ligands for metal ions.
• Polymer Modification: Employed to introduce functional thiol groups into polymer chains for cross-linking or property enhancement.

Basic Information

Product Name	2-Keto-4-Mercaptobutyric Acid
CAS No.	4273-28-3
Molecular Formula	C4H6O3S
Molecular Weight	134.15 g/mol
Synonyms	4-Mercapto-2-oxobutanoic Acid; 4-Thio-2-oxobutanoic Acid; 2-Oxo-4-mercaptobutanoic Acid; 4-Mercapto-2-ketobutyric Acid; α-Keto-γ-mercaptobutyric Acid; 3-Carboxy-3-oxopropyl mercaptan; 2-Ketohomocysteine; 4-Sulfanyl-2-oxobutanoic acid
EINECS	224-255-5

Quality Control

Our 2-Keto-4-Mercaptobutyric Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Our quality commitment ensures the material is suitable for demanding applications in research and synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.