Description

4,5,7-Trihydroxy-3-Phenylcoumarin is a polyphenolic coumarin derivative of significant interest in advanced chemical synthesis and life science research. This compound matters for its role as a versatile synthetic intermediate and a key structural motif in the development of novel bioactive molecules. It is needed by pharmaceutical R&D teams, fine chemical manufacturers, and academic researchers focused on developing new therapeutic agents, natural product analogs, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates with potential anti-inflammatory, antioxidant, or anticancer properties.
• Natural Product Synthesis: Used in the laboratory-scale synthesis and structural modification of complex natural products containing the coumarin scaffold.
• Biochemical Research: Acts as a reference standard or probe in studies investigating enzyme inhibition, receptor binding, or cellular signaling pathways.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced organic materials requiring a functionalized coumarin core.
• Academic & Industrial R&D: Utilized in discovery chemistry for creating new compound libraries and exploring structure-activity relationships (SAR).

Basic Information

Product Name	4,5,7-Trihydroxy-3-Phenylcoumarin
CAS No.	4222-02-0
Molecular Formula	C₁₅H₁₀O₅
Molecular Weight	270.24 g/mol
Synonyms	3-Phenyl-4,5,7-trihydroxycoumarin; 4,5,7-Trihydroxy-3-phenyl-2H-chromen-2-one; 3-Phenylumbelliferone, 4,5,7-trihydroxy-; NSC 407347; 2H-1-Benzopyran-2-one, 4,5,7-trihydroxy-3-phenyl-; 4,5,7-Trihydroxy-3-phenyl-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 4,5,7-Trihydroxy-3-Phenylcoumarin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light, heat, or air should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.