Description

(Iodomethyl)Trimethylsilane is a versatile organosilicon reagent featuring a reactive iodomethyl group. This compound is a critical building block in organic synthesis, enabling efficient carbon-carbon bond formation and functional group transformations. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug molecules, particularly for introducing methylene or modified methylene units.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides by constructing specific carbon frameworks.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for modifying silicone-based polymers and surfaces.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions to install the (iodomethyl)trimethylsilyl moiety.
• Protecting Group Chemistry: Acts as a precursor for reagents used to protect alcohols or other functional groups in multi-step syntheses.
• Laboratory Research: Essential tool in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	(Iodomethyl)Trimethylsilane
CAS No.	4206-67-1
Molecular Formula	C4H11ISi
Molecular Weight	214.12 g/mol
Synonyms	Trimethyl(iodomethyl)silane; Iodotrimethylsilylmethane; (Iodomethyl)trimethylsilicon; (Trimethylsilyl)methyl iodide; Iodomethyltrimethylsilane; TMS-CH2I; NSC 163082
EINECS	224-125-2

Quality Control

Our (Iodomethyl)Trimethylsilane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for research and commercial-scale chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its moisture-sensitive and light-sensitive nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Density (at 20°C)	1.40 - 1.45 g/mL
Refractive Index (n20D)	1.480 - 1.490
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.