Description

1-Methylimidazole-D3 (Ring-D3) is a deuterated analog of 1-methylimidazole, where three hydrogen atoms on the imidazole ring are replaced with deuterium. This isotopic labeling is critical for applications requiring enhanced stability, precise metabolic tracing, or reduced interference in spectroscopic analysis. It is an essential building block and analytical standard for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing and studying compounds using Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS).

Application

• Pharmaceutical Research & Development: Used as a deuterated internal standard or precursor in the synthesis of labeled Active Pharmaceutical Ingredients (APIs) for pharmacokinetic, metabolic, and bioanalytical studies.
• Analytical Chemistry: Serves as a critical standard and reference material in quantitative NMR (qNMR) and Mass Spectrometry to ensure accuracy and method validation.
• Agrochemical Development: Employed in the synthesis of deuterated agrochemicals to study environmental fate, metabolic pathways, and degradation products.
• Material Science: Acts as a precursor or modifier in the development of specialty polymers, ionic liquids, and catalysts where isotopic labeling is required to study mechanism or properties.
• Academic & Industrial Research: A key reagent in mechanistic studies, reaction pathway elucidation, and spectroscopic method development across chemical sciences.

Basic Information

Product Name	1-Methylimidazole-D3 (Ring-D3)
CAS No.	4166-68-1
Molecular Formula	C4H3D3N2
Molecular Weight	85.12 g/mol
Synonyms	1-Methyl-1H-imidazole-2,4,5-d3; N-Methylimidazole-d3 (ring-D3); 1-Methylimidazole-2,4,5-d3; 1-Methyl-1H-imidazole-d3; Deuterated 1-Methylimidazole; N-Methylimidazole-d3; 1-MI-d3; Imidazole, 1-methyl-, 2,4,5-d3-
EINECS	Contact for details

Quality Control

Every batch of 1-Methylimidazole-D3 (Ring-D3) is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, deuterium enrichment (D-enrichment), and identification. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.