Description

1-Amino-2-propanethiol hydrochloride is an organosulfur compound featuring both an amino and a thiol functional group, stabilized as a hydrochloride salt. This unique bifunctional structure makes it a valuable building block and ligand precursor in advanced chemical synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for applications ranging from drug development to materials science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those requiring thiol or amino-thiol motifs.
• Bioconjugation & Protein Modification: Used for introducing thiol-reactive handles or for creating cross-linking agents in antibody-drug conjugates (ADCs) and protein labeling.
• Ligand Synthesis for Catalysis: Acts as a precursor for chelating ligands in transition metal catalysis, useful in asymmetric synthesis.
• Polymer & Material Science: Employed as a monomer or modifier in the production of specialty polymers and functional materials.
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and chemical biology tools.

Basic Information

Product Name	1-Amino-2-propanethiol Hydrochloride
CAS No.	4146-16-1
Molecular Formula	C₃H₉NS•HCl
Molecular Weight	127.63 g/mol
Synonyms	2-Amino-1-propanethiol hydrochloride; 2-Mercaptopropylamine hydrochloride; 1-Amino-2-mercaptopropane hydrochloride; 2-Amino-1-mercaptopropane hydrochloride; 3-Amino-2-propanethiol hydrochloride; β-Mercaptoisopropylamine hydrochloride; DL-2-Amino-1-propanethiol hydrochloride; (±)-2-Amino-1-propanethiol hydrochloride
EINECS	223-977-9

Quality Control

Our 1-Amino-2-propanethiol hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and titration to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We can support development and commercial projects requiring adherence to cGMP or other specific quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to minimize moisture uptake and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.