Description

2-Aminopropane-1-Thiol Hydrochloride is a versatile organosulfur compound with a protected thiol and amine functionality, making it a valuable building block in synthetic organic chemistry. Its primary value lies in its role as a key intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical production. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable source of high-purity chiral intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing β-amino thiol motifs.
• Ligand Synthesis: Used to prepare chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical reactions.
• Peptide Mimetics: Serves as a building block for creating peptide analogs and mimetics with modified biological activity and stability.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized to synthesize probes for studying enzyme mechanisms and protein interactions.
• Material Science: A potential monomer or modifier in the creation of specialized polymers with unique properties.

Basic Information

Product Name	2-Aminopropane-1-Thiol Hydrochloride
CAS No.	4145-98-6
Molecular Formula	C₃H₁₀ClNS
Molecular Weight	127.63 g/mol
Synonyms	2-Amino-1-propanethiol Hydrochloride; 1-Amino-2-mercaptopropane Hydrochloride; 2-Mercaptopropylamine Hydrochloride; β-Aminopropanethiol Hydrochloride; 3-Amino-1-propanethiol Hydrochloride (isomer); 2-Amino-propan-1-thiol HCl; DL-2-Amino-1-propanethiol Hydrochloride; 1-Propanethiol, 2-amino-, hydrochloride
EINECS	223-974-5

Quality Control

Our 2-Aminopropane-1-Thiol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.