Description

4-Hydroxy-3-Propionyl-2H-Chromen-2-One is a specialized coumarin derivative, a key intermediate in the synthesis of more complex organic molecules. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing compounds with specific biological or material properties. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients or advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that leverage the coumarin core structure.
• Fine Chemical Synthesis: Acts as a precursor for synthesizing dyes, fluorescent markers, and other specialty chemicals requiring a functionalized chromene backbone.
• Material Science: Investigated for use in creating organic electronic materials or as a monomer for polymers with specific optical properties.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) conducting studies in medicinal chemistry and synthetic methodology.

Basic Information

Product Name	4-Hydroxy-3-Propionyl-2H-Chromen-2-One
CAS No.	4139-73-5
Molecular Formula	C₁₂H₁₀O₄
Molecular Weight	218.21 g/mol
Synonyms	3-Propionyl-4-hydroxycoumarin; 4-Hydroxy-3-propionylcoumarin; 3-Acetyl-4-hydroxycoumarin (common misnomer); NSC 163022; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-oxopropyl)-; 4-Hydroxy-3-propionyl-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Propionyl-2H-Chromen-2-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.