Description

1-Butyrylimidazole (CAS NO 4122-54-7) is a versatile and highly reactive acylating agent, primarily used for the selective introduction of the butyryl group. Its significance lies in its role as a key synthetic intermediate and reagent in organic synthesis, particularly for the acylation of sensitive substrates under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for prodrug development and molecule functionalization.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific acyl modifications.
• Peptide Chemistry: Employed as an acylating agent for the selective protection of amino groups during peptide synthesis.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialized polyamides, polyimides, and other performance polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Dye and Pigment Manufacturing: Utilized in the synthesis of organic dyes and pigments where butyrylation is a critical step.

Basic Information

Product Name	1-Butyrylimidazole
CAS No.	4122-54-7
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	1-Butanoylimidazole; N-Butyrylimidazole; Butyryl Imidazole; Imidazole, 1-butyryl-; 1H-Imidazole, 1-(1-oxobutyl)-; Butyric acid imidazolide; Butanoyl imidazole
EINECS	223-915-5

Quality Control

Our 1-Butyrylimidazole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR, and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.