Description

6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline is a versatile tetrahydroisoquinoline derivative, a privileged scaffold in medicinal chemistry. This compound matters as a key synthetic intermediate for the development of pharmaceutical agents, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of alkaloid-based drugs, fine chemical production, and advanced organic chemistry research.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential therapeutic agents, including vasodilators and neuroactive compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Alkaloid Synthesis: Used in the semi-synthesis and total synthesis of complex isoquinoline alkaloids and their analogs.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for research and development.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme interactions or receptor binding.
• Academic & Industrial R&D: Fundamental material for exploratory organic synthesis and process chemistry optimization in both academic and industrial settings.

Basic Information

Item	Detail
Product Name	6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	4118-36-9
Molecular Formula	C₁₇H₁₉NO₂
Molecular Weight	269.34 g/mol
Synonyms	1-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-phenyl-3,4-dihydroisoquinoline; NSC 403169; 1-Phenyl-6,7-dimethoxy-3,4-dihydroisoquinoline; 6,7-Dimethoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-phenylisoquinoline
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-1-Phenyl-1,2,3,4-Tetrahydroisoquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and available upon request, detailing all relevant specifications. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.