Description

Methyl 5-Acetylthiophene-2-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both an acetyl and an ester group on a thiophene core, enabling its use in the creation of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing thiophene scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene ring's bioactivity.
• Material Science & Organic Electronics: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Chemical Research & Development: A versatile starting material for academic and industrial R&D in medicinal chemistry and synthetic methodology.
• Dye & Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene unit contributes to color and stability properties.

Basic Information

Product Name	Methyl 5-Acetylthiophene-2-Carboxylate
CAS No.	4101-81-9
Molecular Formula	C8H8O3S
Molecular Weight	184.21 g/mol
Synonyms	5-Acetyl-2-thiophenecarboxylic acid methyl ester; Methyl 5-acetyl-2-thiophenecarboxylate; 2-Thiophenecarboxylic acid, 5-acetyl-, methyl ester; 5-Acetylthiophene-2-carboxylic acid methyl ester; Methyl (5-acetylthiophen-2-yl)carboxylate; 5-Acetyl-2-methoxycarbonylthiophene; 2-Methoxycarbonyl-5-acetylthiophene
EINECS	Contact for details

Quality Control

Our Methyl 5-Acetylthiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.