Description

(Ethoxycarbonylmethyl)Triphenylphosphonium Bromide is a versatile and highly reactive Wittig reagent, a key organophosphorus compound in synthetic organic chemistry. Its primary value lies in its ability to facilitate the efficient synthesis of α,β-unsaturated esters via the Wittig olefination reaction, a cornerstone methodology for constructing carbon-carbon double bonds. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the production of complex molecules and fine chemicals with precise stereochemical control.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing olefinic bonds in active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Production: Used in the synthesis of insecticide and herbicide intermediates that require specific alkene functionalities.
• Fine Chemical & Specialty Chemical Manufacturing: Enables the production of fragrances, flavors, and specialty monomers with defined double bond geometry.
• Academic & Industrial R&D: A fundamental tool in organic synthesis laboratories for method development and novel molecule construction.
• Material Science Precursor: Potential use in synthesizing organic ligands or building blocks for advanced polymeric and electronic materials.

Basic Information

Product Name	(Ethoxycarbonylmethyl)Triphenylphosphonium Bromide
CAS No.	4083-85-6
Molecular Formula	C22H22BrO2P
Molecular Weight	429.29 g/mol
Synonyms	(Carbethoxymethyl)triphenylphosphonium bromide; Ethyl (triphenylphosphoranylidene)acetate bromide; Triphenylphosphonium bromoacetate ethyl ester; (Ethoxycarbonylmethyl)triphenylphosphonium bromide; Wittig reagent for ethyl acrylate; ETPB; Phosphonium, (carbethoxymethyl)triphenyl-, bromide
EINECS	223-807-4

Quality Control

Our (Ethoxycarbonylmethyl)Triphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, moisture content, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.