Description

2-Thiopheneacetyl Chloride, α-Oxo- (9Ci) is a high-purity, reactive organosulfur building block. This compound is valued for its role as a versatile acylating agent and key synthon in the synthesis of complex heterocyclic molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of thiophene-containing drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and conductive materials.
• Chemical Research (R&D): Employed in academic and industrial laboratories for method development and the exploration of new heterocyclic chemistry.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, α-Oxo- (9Ci)
CAS No.	4075-60-9
Molecular Formula	C6H3ClO2S
Molecular Weight	174.60 g/mol
Synonyms	2-(Chlorooxoacetyl)thiophene; 2-Thenoic acid, chlorooxo-; 2-Thiopheneglyoxylic acid chloride; 2-Thiopheneglyoxyloyl chloride; 2-Thienylglyoxylic acid chloride; 2-Thienylglyoxyloyl chloride; α-Oxo-2-thiopheneacetyl chloride; 2-(Chlorooxoacetyl)thiophene
EINECS	223-787-4

Quality Control

Every batch of 2-Thiopheneacetyl Chloride, α-Oxo- (9Ci) is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A detailed Certificate of Analysis (COA) including purity (HPLC/GC), identity (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.