Description

(4-Acetyl-Phenyl)-Phosphonic Acid is a high-purity organophosphorus compound featuring a phosphonic acid group linked to a para-acetylphenyl moiety. This unique bifunctional structure makes it a versatile and valuable building block for synthesizing advanced materials and specialty chemicals. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting bone diseases or requiring metal-chelating properties.
• Agrochemical Synthesis: Used to develop new herbicides, plant growth regulators, and fungicides by incorporating the phosphonic acid moiety for enhanced bioactivity and systemic movement.
• Metal-Organic Framework (MOF) Precursor: Acts as an organic linker for constructing porous coordination polymers and MOFs with specific pore geometries and surface functionalities for gas storage or catalysis.
• Surface Modification Agent: Employed to functionalize metal oxide surfaces (e.g., titanium dioxide, iron oxide) to improve adhesion, corrosion resistance, or biocompatibility in coatings and composites.
• Ligand for Catalysis: Functions as a chelating ligand for transition metals, creating catalysts for organic transformations such as cross-coupling reactions or asymmetric synthesis.
• Flame Retardant Synergist: Incorporated into polymer formulations, where the phosphonic acid group can promote char formation and enhance flame retardancy.

Basic Information

Product Name	(4-Acetyl-Phenyl)-Phosphonic Acid
CAS No.	4042-61-9
Molecular Formula	C8H9O4P
Molecular Weight	200.13 g/mol
Synonyms	p-Acetylphenylphosphonic Acid; 4-Acetylbenzenephosphonic Acid; (4-Acetylphenyl)phosphonic Acid; 1-(4-Phosphonophenyl)ethanone; 4-Acetylphenylphosphonate; p-Acetylphenylphosphonate; Ethanone, 1-[4-(phosphono)phenyl]-; 4042-61-9
EINECS	Contact for details

Quality Control

Every batch of (4-Acetyl-Phenyl)-Phosphonic Acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality control protocol includes identification by spectroscopic methods, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 2.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.