Description

Methysticin CAS NO 495-85-2 is a bioactive kavalactone, a class of compounds primarily found in the kava plant (*Piper methysticum*). This compound is of significant interest for its potential physiological effects and serves as a key reference standard in analytical and research settings. It is essential for manufacturers and researchers in the nutraceutical, pharmaceutical, and analytical chemistry industries who require high-purity materials for product development, quality control, and scientific studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of kava-based products and botanical extracts.
• Nutraceutical & Dietary Supplement Research: A critical component in the research and development of standardized kava extracts, where specific kavalactone content is required for efficacy and consistency.
• Analytical Chemistry: Serves as a primary standard for calibrating HPLC, LC-MS, and other chromatographic systems in methods developed to quantify kavalactones.
• Biochemical & Pharmacological Studies: Employed in *in vitro* and *in vivo* research to investigate the mechanisms of action, metabolism, and safety profile of kavalactones.
• Quality Control Laboratories: Utilized by QC labs in the herbal supplement industry to verify the authenticity and potency of raw materials and finished goods against established specifications.

Basic Information

Product Name	Methysticin
CAS No.	495-85-2
Molecular Formula	C15H14O5
Molecular Weight	274.27 g/mol
Synonyms	5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one; (+)-Methysticin; (E)-Methysticin; Kawain; Kavalactone Methysticin; 4-Methoxy-6-[(E)-styryl]-5,6-dihydro-2-pyrone; 6-Styryl-4-methoxy-5,6-dihydro-2-pyrone
EINECS	207-806-7

Quality Control

Our Methysticin is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC, to ensure it meets the high standards required for research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.