Description

Nodakenetin is a bioactive coumarin derivative, also known as nodakenin aglycone, primarily sourced from the roots of *Angelica* species. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient (API) in research and development. It is essential for professionals in the pharmaceutical, nutraceutical, and advanced chemical synthesis sectors who require high-purity phytochemicals for analytical and formulation purposes.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Bioactivity Research: Serves as a critical compound in pharmacological studies investigating anti-inflammatory, neuroprotective, and antioxidant mechanisms.
• Natural Product Isolation & Synthesis: Acts as a precursor or intermediate in the semi-synthesis of more complex coumarin-based drug candidates.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements where standardized botanical extracts are required for consistent efficacy.
• Cosmeceutical Development: Evaluated for potential use in skincare formulations targeting inflammation and oxidative stress.

Basic Information

Product Name	Nodakenetin
CAS No.	495-32-9
Molecular Formula	C14H14O4
Molecular Weight	246.26 g/mol
Synonyms	Nodakenetin; Nodakenin aglycone; 7-Hydroxy-8-[(2R,3R)-2,3-dihydroxy-3-methylbutyl]coumarin; Decursinol; (R)-Decursinol; Columbianetin; 8-(2,3-Dihydroxy-3-methylbutyl)-7-hydroxy-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our Nodakenetin is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms for identity and purity verification. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are available for every batch upon request, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.