Description

L-(-)-Ephedrine is a naturally occurring alkaloid and a potent sympathomimetic amine, serving as a key chiral building block and active pharmaceutical ingredient. Its stereochemistry is critical for biological activity, making it essential for producing enantiomerically pure pharmaceuticals. This high-purity compound is primarily sought by the pharmaceutical, nutraceutical, and fine chemical synthesis industries for its decongestant and bronchodilator properties.

Application

• Pharmaceutical API: Core ingredient in prescription and over-the-counter (OTC) medications for asthma, bronchitis, and nasal congestion.
• Decongestant Formulations: Used in cough, cold, and allergy relief syrups, tablets, and nasal sprays.
• Bronchodilator Production: A precursor in the synthesis of more advanced bronchodilating agents.
• Chiral Intermediate: Serves as a starting material for the asymmetric synthesis of complex drug molecules requiring specific stereochemistry.
• Weight Management Supplements: Historically used as a component in certain dietary supplements, subject to strict regional regulations.
• Chemical Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing.

Basic Information

Product Name	L-(-)-Ephedrine
CAS No.	492-41-1
Molecular Formula	C10H15NO
Molecular Weight	165.23 g/mol
Synonyms	(-)-Ephedrine; L-Ephedrine; (1R,2S)-(-)-Ephedrine; Ephedrine; 2-Methylamino-1-phenylpropan-1-ol; Erythro-(-)-ephedrine; Ephedrine alkaloid; 1R,2S-(-)-Ephedrine
EINECS	207-757-1

Quality Control

Our L-(-)-Ephedrine is manufactured under strict quality management systems. It undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for pharmaceutical applications. Certificates of Analysis (COA) detailing assay, optical rotation, impurity profile, and residual solvents are provided with each batch to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White crystalline powder or granules
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Specific Optical Rotation	-33° to -36° (c=5 in H2O)
Related Substances (HPLC)	Total impurities ≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.