Description

7-Methoxy-8-(3,3-Dimethylglycidyl)-2H-1-Benzopyran-2-One is a specialized coumarin derivative with a reactive epoxide functional group, making it a valuable synthetic intermediate. This compound is critical for the development of advanced active pharmaceutical ingredients (APIs) and fine chemicals due to its ability to undergo ring-opening reactions and form covalent bonds. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anticoagulant, anti-inflammatory, and anticancer drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its fused heterocyclic structure.
• Fine Chemical Production: Serves as a precursor for dyes, fluorescent markers, and other high-value specialty chemicals.
• Biochemical Research: Employed in proteomics and molecular biology as a potential scaffold for designing enzyme inhibitors or fluorescent probes.
• Material Science: Investigated for use in polymer modification and as a cross-linking agent due to its reactive epoxide moiety.

Basic Information

Product Name	7-Methoxy-8-(3,3-Dimethylglycidyl)-2H-1-Benzopyran-2-One
CAS No.	489-53-2
Molecular Formula	C₁₅H₁₆O₅
Molecular Weight	276.29 g/mol
Synonyms	7-Methoxy-8-(2,3-epoxy-3-methylbutyl)coumarin; 7-Methoxy-8-(2,3-epoxy-3-methylbutyl)-2H-chromen-2-one; 8-(2,3-Epoxy-3-methylbutyl)-7-methoxycoumarin; 7-Methoxy-8-(3-methyl-2,3-epoxybutyl)coumarin; 7-Methoxy-8-(3-methyloxiran-2-ylmethyl)coumarin; 7-Methoxy-8-(3,3-dimethyloxiranylmethyl)chromen-2-one; 7-Methoxy-8-(3,3-dimethylglycidyl)coumarin
EINECS	207-688-6

Quality Control

Our 7-Methoxy-8-(3,3-Dimethylglycidyl)-2H-1-Benzopyran-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.